Treatment of the ester 2d with ethyl acrylatelO in the presence of sodium ethoxide gave a 75% yield of the ester 2e, which was readily converted to the half-ester 2f by partial hydrolysis (74% yield). Cyclization of 2f by treatment with anhydrous HF afforded the keto ester 3a in 71% yield. Reduction of the ester 3a by the Clemmensen method'l gave the ester 3c (87% yield), which was dehydrogenated with DDQ to IC in 65% yield. Reduction of the ...
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