The Journal of Organic Chemistry

. alpha.-Halogenation of certain ketones

B Modarai, E Khoshdel

Index: Modarai,B.; Khoshdel,E. Journal of Organic Chemistry, 1977 , vol. 42, # 22 p. 3527 - 3531

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Citation Number: 11

Abstract

A variety of a-halo and a-gem-dihalo ketones, including the fluoro and iodo compounds, have been prepared. The scope and limitations of their syntheses have been studied. Every attempt at the preparation of 3, 3-difluoro-2-butanone gave biacetyl as the only product, although the analogous gem-difluoropropiophenone was conveniently obtained. The synthesis of the difluorobutanone could, however, be effected with the introduction of an ...