Tetrahedron Letters

A general route for constructing difluoromethyl ethers

Y Hagooly, O Cohen, S Rozen

Index: Hagooly, Youlia; Cohen, Or; Rozen, Shlomo Tetrahedron Letters, 2009 , vol. 50, # 4 p. 392 - 394

Full Text: HTML

Citation Number: 13

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Chlorodifluoromethyl ethers are easily obtained from the corresponding alcohols. These ethers, when treated with tributyltin hydride, produce difluoromethyl ethers in high yields. ... Of all the hydrogen radical sources, tributyltin hydride is one of the best. Thus, refluxing chlorodifluoromethyl octyl ...