Some Pyridyl-and Thiophenyl-Substituted 1, 2, 4-Triazolo [3, 4-b] 1, 3, 4-thiadiazole Derivatives as Potent Antibacterial

…, M Hanif, M Rafiq, M Saleem, S Zaib…

Index: Maqsood, Muhammad Rizwan; Hanif, Muhammad; Rafiq, Muhammad; Saleem, Muhammad; Zaib, Sumera; Khan, Aftab Ahmed; Iqbal, Mazhar; Iqbal, Jamshed; Rama, Nasim Hasan; Seo, Sung-Yum; Lee, Ki-Hwan Bulletin of the Korean Chemical Society, 2012 , vol. 33, # 12 p. 4180 - 4184

Full Text: HTML

Citation Number: 4

Abstract

Abstract The target compounds 6-11a-e were synthesized by condensing 4-amino-5-aryl-3H- 1, 2, 4-triazole-3-thiones 5a-f with various aromatic carboxylic acids in the presence of phosphorous oxychloride. The structures of newly synthesized compounds were characterized by IR, NMR, NMR, elemental analysis and mass spectrometric studies. All the synthesized compounds were screened for their antibacterial activity. Almost all the tested ...