New Calcium??Selective Smart Contrast Agents for Magnetic Resonance Imaging

…, H Uh, M Beyerlein, ME Maier, S Petoud…

Index: Verma, Kirti Dhingra; Forgacs, Attila; Uh, Hyounsoo; Beyerlein, Michael; Maier, Martin E.; Petoud, Stephane; Botta, Mauro; Logothetis, Nikos K. Chemistry - A European Journal, 2013 , vol. 19, # 52 p. 18011 - 18026

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Citation Number: 7

Abstract

Abstract Calcium plays a vital role in the human body and especially in the central nervous system. Precise maintenance of Ca 2+ levels is very crucial for normal cell physiology and health. The deregulation of calcium homeostasis can lead to neuronal cell death and brain damage. To study this functional role played by Ca 2+ in the brain noninvasively by using magnetic resonance imaging, we have synthesized a new set of Ca 2+-sensitive smart ...