Synthesis and thromboxane A 2 antagonistic activity of indane derivatives

…, T Iwakuma, R Sato, T Kurimoto, K Yoshida

Index: Shinozaki; Sato; Iwakuma; Kurimoto; Yoshida Bioorganic and medicinal chemistry letters, 1999 , vol. 9, # 3 p. 401 - 406

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Citation Number: 13

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new series of indane derivatives were prepared and evaluated for their thromboxane A 2 (TXA 2 , 1) antagonistic activity. Among these compounds, 24a (Z-335) was found to be a potent TXA 2 antagonist in oral administration. ... A new series of indane derivatives were ...