The Journal of Organic Chemistry

Chiral HPLC (high-performance liquid chromatographic) stationary phases. 4. Separation of the enantiomers of bi-. beta. naphthols and analogs

WH Pirkle, JL Schreiner

Index: Pirkle, William H.; Schreiner James L. Journal of Organic Chemistry, 1981 , vol. 46, p. 4988 - 4991

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Citation Number: 125

Abstract

The enantiomers of a number of bi-@-naphthols and analogues thereof are readily separable upon an ionically bonded chiral high-pressure liquid chromatographic stationary phase. The elution orders of the enantiomers are related to absolute configuration by a chiral recognition rationale that also provides insight into the efficiency of the chiral recognition process. The method is advocated as a means for assigning absolute ...