Abstract 2-Methyltetrahydroanthra [2, 3-d] isothiazole-3, 5, 10-trione and 2-R- tetrahydroanthra [2, 1-d] isothiazole-3, 6, 11-triones were synthesized by the reactions of 3- chloro-9, 10-dioxo-9, 10-dihydroanthracene-2-carboxamide and 1-nitro-9, 10-dioxo-9, 10-