e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Polycyclic N??heterocyclic compounds, part 67: Reaction of 6, 7??substituted N??(quinazolin??4??yl) amidine derivatives with hydroxylamine hydrochloride: Formation of in …
Abstract Reactions of N-(quinazolin-4-yl) amidines and their amide oximes with hydroxylamine hydrochloride gave cyclization products that were formed by an initial ring cleavage of the pyrimidine component followed by a ring closure formation of 1, 2, 4- oxadiazole to give N-[2-([1, 2, 4] oxadiazol-5-yl) phenyl] formamide oximes. All isolated products were evaluated for in vitro inhibitory activity on the formation of pentosidine, ...
