Synthesis and 1 H and 13 C NMR spectra of sulfur derivatives of pyrazine derived from amidation product of 2-chloropyrazine and 6-chloro-2-pyrazinecarbonitrile. …

…, K Palát, A Lyčka, Ž Odlerová

Index: Dlabal, Karel; Palat, Karel; Lycka, Antonin; Odlerova, Zelmira Collection of Czechoslovak Chemical Communications, 1990 , vol. 55, # 10 p. 2493 - 2501

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Citation Number: 22

Abstract

Abstract Homolytic amidations of 2-chloropyrazine and 6-chloropyrazine-2-carbonitrile have been carried out to obtain products which have been used to prepare sulfur derivatives of pyrazine as potential tuberculostatic agents. The 1 H and 13 C NMR spectra of the products have been measured and interpreted, and the antituberculotic activity has been evaluated.