Synthesis, characterization, and antimicrobial activities of clubbed [1, 2, 4]??oxadiazoles with fluorobenzimidazoles

…, MU Shaikh, RP Kale, AR Ghawalkar…

Index: Jadhav, Ganesh R.; Shaikh, Mohammad U.; Kale, Rajesh P.; Ghawalkar, Anand R.; Gill, Charansingh H. Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 5 p. 980 - 987

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Citation Number: 7

Abstract

After nitrogen, fluorine occupies the position of second favorite heteroelement in life science- oriented research. Over 10% of newly registered pharmaceutical drugs and some 40% of newly registered agrochemicals contain one or more fluorine atoms [1]. Fluorine containing benzimidazoles, which show promising biological activities, are well documented in the literature. Some of these are like Astemizole (antiallergic, anti-histaminic), Lansoprazole ( ...