Design, synthesis and determination of antifungal activity of 5 (6)-substituted benzotriazoles

…, B Kocsis, E Kocsis, SM Graham, AR Warren…

Index: Patel, Pallav D.; Patel, Maulik R.; Kocsis, Bela; Kocsis, Erika; Graham, Steven M.; Warren, Andrew R.; Nicholson, Stacia M.; Billack, Blase; Fronczek, Frank R.; Talele, Tanaji T. European Journal of Medicinal Chemistry, 2010 , vol. 45, # 6 p. 2214 - 2222

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Citation Number: 18

Abstract

In an effort to find inhibitors that are effective against both Candida and Aspergillus spp., a series of 5 (6)-(un) substituted benzotriazole analogs, represented by compounds 3a–3h and 3b′–3f′, were prepared using a crystalline oxirane intermediate 1 previously ...