Carbohydrate Research

Improved synthesis of 2, 5-anhydro-d-allononitrile

HS El Khadem, J Kawai

Index: El Khadem, Hassan S.; Kawai, Joshua Carbohydrate Research, 1983 , vol. 115, p. 131 - 138

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Citation Number: 4

Abstract

Abstract Two types of mixed ester of β-d-ribofuranose were synthesized. The first had the same groups attached to O-1, 2, and 3, and the second had the same groups attached to O- 2, 3, and 5. The three esters obtained in the highest yields, starting from d-ribose, were then converted into the halides and nitriles. Of the esters studied, the best suited for conversion into the nitrile was 1-O-acetyl-2, 3, 5-tri-Op-toluyl-β-d-ribofuranose, which afforded 2, 5- ...