Efficient tetrahydropyranylation of alcohols and detetrahydropyranylation reactions in the presence of catalytic amount of trichloroisocyanuric acid (TCCA) as a safe, …

H Firouzabadi, N Iranpoor…

Index: Firouzabadi, Habib; Iranpoor, Nasser; Hazarkhani, Hassan Synthetic Communications, 2004 , vol. 34, # 19 p. 3623 - 3630

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Citation Number: 15

Abstract

Tetrahydropyranylation of alcohols and phenols is a useful tool for masking hydroxy functional groups for further manipulation in organic synthesis. This transformation has found important synthetic applications because of the stability of the tetrahydropyranyl derivatives towards basic media, Grignard reagents, and reactions involving oxidation and reduction by inorganic hydride transfer agents.56. Greene , TW and Wuts , PGM 1991. Protective Groups in Organic ...