The multifunctional cytochrome P450 monooxygenases P450-1 and P450-2 from Fusarium fujikuroi catalyze the formation of GA14 and GA4, respectively, in the gibberellin (GA)- biosynthetic pathway. However, the activity of these enzymes is qualitatively and quantitatively different in mutants lacking the NADPH: cytochrome P450 oxidoreductase (CPR) compared to CPR-containing strains. 3β-Hydroxylation, a major P450-1 activity in ...