A novel and efficient synthesis of a highly active analogue of clasto-lactacystin β-lactone

F Soucy, L Grenier, ML Behnke…

Index: Journal of the American Chemical Society, , vol. 121, # 43 p. 9967 - 9976

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Citation Number: 87

Abstract

... Journal of the ... 1999, 121 (43), pp 9967–9976. DOI: 10.1021/ja991175f. Publication Date (Web): October 13, 1999. Copyright © 1999 American Chemical Society. ... Having the aldolate 9 with the correct oxidation state at C-8 allows us to avoid protection/deprotection steps and/or ...