The enantiospecific synthesis of chromanes and isochromanes using a variant of an intramolecular Nicholas reaction

E Tyrrell, K Mazloumi, D Banti, P Sajdak, A Sinclair…

Index: Tyrrell, Elizabeth; Mazloumi, Khatebeh; Banti, Donatella; Sajdak, Paulina; Sinclair, Alex; Le Gresley, Adam Tetrahedron Letters, 2012 , vol. 53, # 33 p. 4280 - 4282

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Citation Number: 9

Abstract

The enantiospecific synthesis of chromanes and isochromanes obtained from an intramolecular Nicholas cyclisation reaction is discussed. During the course of this study we observed the formation of chroman-4-ones from a CAN deprotection step of a dioxolane and this is also discussed.