Tetrahedron letters

Synthesis and structure of diastereomers of pentenocin B produced by Trichoderma hamatum FO-6903

…, H Fujiwara, K Maeda, M Habara, N Sakaedani…

Index: Ohira, Susumu; Fujiwara, Hiroyuki; Maeda, Kiyomi; Habara, Masaharu; Sakaedani, Naomi; Akiyama, Megumi; Kuboki, Atsuhito Tetrahedron Letters, 2004 , vol. 45, # 8 p. 1639 - 1641

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Citation Number: 8

Abstract

All diastereomers of pentenocin B, an inhibitor of interleukin-1β converting enzyme produced by Trichoderma hamatum FO-6903, were synthesized in chiral forms starting from l-threonine. Absolute configurations of natural pentenocin B were clarified to be 4S, 5R, and 6R.