Direct interaction of indolylzinc chloride with 2, 5-dichloro-3, 4-dinitrothiophene (4) produced 2, 5-bis (indol-3-yl)-3, 4-dinitrothiophene (5) together with 3-(5-chloro-3, 4-dinitrothien-2-yl) indole (6). Interaction of the latter compound with 1-methylpiperazine gave 3-[4, 5-di (4- methylpiperazin-1-yl)-3-nitrothien-2-yl] indole (7), as the expected SN-Ar (addition- elimination) di-substitution product, together with 3-[5-(4-methylpiperazin-1-yl)-3-nitrothien ...
