A new strategy for the synthesis of oxide-containing fragments of morphine has been developed. Thus, the tricyclic (ANO) morphine fragment spiro [7-methoxybenzofuran-3 (2H), 4′-1′-methylpiperidine](1) was obtained as the sole product via an intramolecular radical cyclization of 4-[(2′-bromo-6′-methoxyphenoxy) methyl]-1-methyl-1, 2, 5, 6,- tetrahydropyridine (9); while the tetracyclic (ACNO) fragment 9-methoxy-3-methyl-2, 3, 4, ...
