The stereoselective synthesis of 4'-β-thioribonucleosides via the Pummerer reaction

T Naka, N Minakawa, H Abe, D Kaga…

Index: Hancox, E. Louise; Walker, Richard T. Nucleosides and Nucleotides, 1996 , vol. 15, # 1-3 p. 135 - 148

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Citation Number: 85

Abstract

... 1 and varicella zoster virus, BVDU is rapidly metabolized to the inactive E-5-(2 ... 5 In contrast, 4'-thioBVDU is resistant to pyrimidine nucleoside phosphorylase, and showed a higher ... including the replacement of the furanose ring oxygen in biologically active nucleosides with a ...