Organic letters

Carboxylation with CO2 via Brook Rearrangement: Preparation of α-Hydroxy Acid Derivatives

T Mita, Y Higuchi, Y Sato

Index: Organic Letters, , vol. 16, # 1 p. 14 - 17

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Citation Number: 16

Abstract

... Organic Letters. ... next conceivable target is the synthesis of α-hydroxy acids, which are also very useful building blocks in organic synthesis.(5 ... a 5:2 diastereomeric ratio, suggesting that this γ-carboxylation might proceed through the 1,4-Brook rearrangement pathway (eq 5).(16). ...