Chiral 1, 5-diaza-cis-decalins have been examined as ligands in the enantioselective oxidative biaryl coupling of substituted 2-naphthol derivatives. Under the optimal conditions employing 2.5-10 mol% of a 1, 5-diaza-cis-decalin copper (II) catalyst with oxygen as the oxidant, enantioselective couplings (44-96% ee) could be achieved for a range of 3- substituted 2-naphthols including the ester, ketone, phosphonyl, and sulfonyl derivatives. ...
