Siiifamoyl suhstitiitccl 2H-1, L',~-bt, iizotliiadiaziiic. 1 I-diosidrs. inc: luding tlic 3, l-diliydro compounds, arc'a\ vc~ lI kiiowii class of orally effective diuretic agcxiits.'1 h 1 y of them also show ai1 aiitiliyperteiisive effect sild are used clinically in the treatment of mild liyperteii- sioii.?; llthough the precise mcchaiiism of this actioii is not kiiowii, it has geiierally hem assumed to be related to tlic diuretic and iiatriurctic properties of the com-poiitids. 3 How! ...
