Journal of the Chemical Society C: Organic

The reactions of 2-aminothiazoles and 2-aminobenzothiazoles with propiolic acid and its esters

DW Dunwell, D Evans

Index: Dunwell,D.W.; Evans,D. Journal of the Chemical Society [Section] C: Organic, 1971 , p. 2094 - 2097

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Citation Number: 22

Abstract

The main products from the title reactions were 7H-thiazolo [3, 2-a] pyrimidin-7-ones (IV) and 2H-pyrimido-[2, 1-b] benzothiazol-2-ones (V). Treatment of some of these with primary and secondary aliphatic amines yielded 2-(β-aminoacryloyl) imino-Δ4-thiazolines (X) and the corresponding benzo-analogues (XI).