Heterocycles

Synthetic approaches to benzofuran containing insulin sensitivity enhancer compounds for treatment of type II diabetes

BE Huff, CL Leffelman, ME LeTourneau, KA Sullivan…

Index: Heterocycles, , vol. 45, # 7 p. 1363 - 1384

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Citation Number: 8

Abstract

The search for Insulin Sensitivity Enhancer (ISE) compounds, for potential use in the treatment of Type II diabetes, has led to the synthesis of compounds that contain a benzofuran spacer between an aryloyl substituent and a 2,4-thiazolidinedione pharmacophore. Sequential ...