Suitably functionalised pyrimidines as potential antimycotic agents

N Agarwal, SK Raghuwanshi, DN Upadhyay…

Index: Agarwal, Nidhi; Raghuwanshi, Sandeep K.; Upadhyay; Shukla; Ram, Vishnu J. Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 8 p. 703 - 706

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Citation Number: 60

Abstract

The incidence of invasive fungal infections has largely been attributed to the rising number of immunocompromised patients. The commonest cause of invasive fungal infections in human are the species of Aspergillus followed by Candida and Cryptococcus neoformans. The superficial fungal infections, very common in major populations is caused by species of Trichophyton mentagrophytes, T. rubrum and Sporothrix schenckii. Because of a wide prevelence of ...