The development of cyclic sulfolanes as novel and high-affinity P2 ligands for HIV-1 protease inhibitors

AK Ghosh, HY Lee, WJ Thompson…

Index: Journal of Medicinal Chemistry, , vol. 37, # 8 p. 1177 - 1188

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Citation Number: 58

Abstract

... The desired cis isomer 15 was separated from the mixture by silica gel chromatography with 25 % ethyl acetate in hexane. 0022-2623/94/1837-117'7$04.50/0 0 1994 American Chemical Society Page 2. 1178 Journal of Medicinal Chemistry, 1994, Vol. 37, No. 8 ...