Fluoride-mediated selective cross-coupling reactions of alkyl halides and trimethyl (perfluoroalkyl) silanes, Me 3 SiR f (R f= CF 3, C 2 F 5) in the absence of any …

…, D Naumann, S Quadt, S Buslei, YL Yagupolskii…

Index: Tyrra, Wieland; Naumann, Dieter; Quadt, Silke; Buslei, Sigrid; Yagupolskii, Yurii L.; Kremlev, Mikhail M. Journal of Fluorine Chemistry, 2007 , vol. 128, # 7 p. 813 - 817

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Citation Number: 13

Abstract

C n H 2 n + 1 X 1 + M e 3 SiC F 3 + [ Cat ] F ⟶ − 18 ° C to r . t . DME C n H 2 n + 1 C F 3 2 + M e 3 SiF + [ Cat ] X , X = Br , I ; Cat = NM e 4 , S ( NM e 2 ) 3 , Cs ( 15 -Crown- 5 ) 2 ; C n H 2 n + 1 I 1 + M e 3 Si C 2 F 5 + [ Cs ( 15 -Crown- 5 ) 2 ] F ⟶ − 18 ° C to r . t . DME C n H 2 n + 1 C 2 F 5 3 + M e 3 SiF + [ Cs ( 15 -Crown- 5 ) 2 ] I . ... Reactions of trimethyl(perfluoroalkyl)silanes are widely applied in organic and element organic synthesis with a variety of substrates [1]. ...