(1,3-Dioxo-1,3-dihydro-2H-isoindoll-2-yl)(phenyl)methyl acetate 2a: a mixture of 1a (1 g, 1 equiv., 4.21 mmol), NBS (1.12 g, 1.5 equiv., 6.32 mmol), NaOAc (0.52 g, 1.5 equiv., 6.32 mmol) and HOAc (0.38 g, 1.5 equiv., 6.32 mmol) in chlorobenzene (25 ml) was refluxed for 12 h. After cooling, chlorobenzene was removed under reduced pressure. The crude product was extracted with ether and concentrated. The resulting mixture was applied to column ...
