Synthetic Communications

Clay catalysis: dry condensation of 3-methyl-1-phenyl-5-pyrazolone with aldehydes under microwave irradiation

D Villemin, B Labiad

Index: Villemin, Didier; Labiad, Bouchta Synthetic Communications, 1990 , vol. 20, # 20 p. 3213 - 3218

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Citation Number: 31

Abstract

ISMRa ,URA480 CNRS,Universite' de Caen, F I4050 Caen cedex, France. ... ABSTRACT: 3-Methyl- 1 -phenyl-5-pyrazolone (1) and arylcarboxyaldehydes (2) were condensated to 1 -phenyl-3-methyl-4-(arylmethylene)-S-pyrazoIoiie ... The derivatives of the pyrazolone are important class of antipyretic and analgesic compounds ( antipyrine, amidopyrine, phenylbutazolone). l-Phenyl-3-methyl-4- (arylmethylene)-5-pyrazolones (3) are useful intermediate in ...