2-[2-Substituted-3-(3, 4-dichlorobenzylamino) propylamino]-1H-quinolin-4-ones as Staphylococcus aureus methionyl-tRNA synthetase inhibitors

T Kang, EJ Yoon, EC Choi, S Kim, J Lee

Index: Farhanullah; Kang, Taehee; Yoon, Eun-Jung; Choi, Eun-Chil; Kim, Sunghoon; Lee, Jeewoo European Journal of Medicinal Chemistry, 2009 , vol. 44, # 1 p. 239 - 250

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Citation Number: 20

Abstract

New analogues of 2-[2-substituted-3-(3, 4-dichlorobenzylamino) propylamino] quinolin-4- ones, 26a, 26b, 31a–e, 34, 35, 38 and 40, have been synthesized and evaluated against Staphylococcus aureus methionyl-tRNA synthetase. All of the synthesized compounds ...