e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Tetrahedral onsager crosses for solubility improvement and crystallization bypass
I Aujard, JP Baltaze, JB Baudin, E Cogne…
Index: Aujard; Baltaze; Baudin; Cogne; Ferrage; Jullien; Perez; Prevost; Lin Mao Qian; Ruel Journal of the American Chemical Society, 2001 , vol. 123, # 34 p. 8177 - 8188
Pure organic molecules exhibiting a suitable concave rigid shape are expected to give porous glasses in the solid state. Such a feature opens new opportunities to avoid crystallization and to improve molecular solubility in relation to the high internal energy of these solid phases. To quantitatively explore the latter strategy, a series of rigid tetrahedral conjugated molecules n C and the corresponding models n R have been synthesized. ...