Tetrahedron letters

The synthesis of amino acids by reaction of an electrophilic glycine cation equivalent with carbon nucleophiles

MJ O'Donnell, JB Falmagne

Index: O'Donnell, Martin J.; Falmagne, Jean-Bernard Tetrahedron Letters, 1985 , vol. 26, # 6 p. 699 - 702

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Citation Number: 32

Abstract

Abstract Acetate 1, a glycine cation equivalent, is reacted with organocopper reagents to yield products 2, which can readily be converted to the higher amino acids. This method provides access to aryl-substituted amino acids as well as amino acids containing a β- ...