An improved process for the production of rivastigmine tartrate, a cholinesterase inhibitor

…, AV Kumar, C Praveen, K Mukkanti…

Index: Reddy, Vajrala Venkata; Naga, Mandava Venkata; Rao, Brahmeswara; Ganesh, Varanasi; Kumar, Adla Vijaya; Praveen, Cherukupally; Mukkanti, Khagga; Reddy, Ganta Mahesh; Reddy, Ganta Madhusudhan Letters in Organic Chemistry, 2010 , vol. 7, # 2 p. 149 - 154

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Abstract

An improved and scalable process for the production of rivastigmine tartrate is reported. The improved process provides rivastigmine tartrate at considerably lower cost and allows the omission of hazardous chemicals. The overall yield is increased from 4.66%(reported process) to 17% with the improved process.