5-Chloro-N-(4-methoxy-3-piperazin-1-yl-phenyl)-3-methyl-2-benzothiophenesulfon-amide (SB-271046): a potent, selective, and orally bioavailable 5-HT6 receptor …

SM Bromidge, AM Brown, SE Clarke…

Index: Journal of Medicinal Chemistry, , vol. 42, # 2 p. 202 - 205

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Citation Number: 171

Abstract

... The structure of 1 was deemed to be readily amenable to exploration of structure-activity relationships (SAR) by rapid parallel synthesis, and it was therefore selected as the starting point for a chemical program. ... Journal of Medicinal Chemistry, 1999, Vol. 42, No. 2 205