Tetrahedron

C-Metallated reformatsky intermediates. Structure and reactivity.

F Orsini, F Pelizzoni, G Ricca

Index: Orsini,F.; Pelizzoni,F. Tetrahedron, 1984 , vol. 40, p. 2781

Full Text: HTML

Citation Number: 40

Abstract

13C-NMR analysis of the Reformatsky intermediates from t-bu tyl-α-bromo acetate, t-bu tyl-α- bromo isobutyrate and t-bu tyl-α-bromo pro pionate have evidenced C-metallated species. Their ability to act as nu cleophilic reagents under mild conditions and their selectivity towards ha logen-and oxygen containing electrophiles is reported.