Antimony-Templated Macrolactamization of Tetraamino Esters. Facile Synthesis of Macrocyclic Spermine Alkaloids,(±)-Buchnerine,(±)-Verbacine,(±)-Verbaskine, and …

K Ishihara, Y Kuroki, N Hanaki, S Ohara…

Index: Ishihara; Kuroki; Hanaki; Ohara; Yamamoto Journal of the American Chemical Society, 1996 ,  vol. 118,  # 6  p. 1569 - 1570

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Citation Number: 49

Abstract

The macrocyclic lactams containing the biogenetic base spermine are of particular interest as synthetic targets for the organic chemist in view of the broad activity which has been established for spermine-containing compounds in biological systems and because of the structural complexity of the molecules themselves. 1 We have been interested in the possibility of metal-templated cyclization of spermine derivatives which would result in the ...