The 2-arylpropionic acids are a class of non-steroidal antiinflammatory agents that have remained an area of intense study.'Often only one enantiomer is biologically active. Therefore, the asymmetric synthesis of this class of compounds has received considerable attention. While many approaches have been developed, the majority lack simplicity and high stereoselectivity. 2 We wish to report an exciting find in the asymmetric ...
