Tetrahedron letters

An efficient synthesis of 3-acylcarbazoles and observations on the further elaboration of these compounds to 6h-pyridocarbazoles

I Hogan, P Jenkins, M Sainsbury

Index: Hogan, Iain; Jenkins, Paul; Sainsbury, Malcolm Tetrahedron Letters, 1988 ,  vol. 29,  # 49  p. 6505 - 6508

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Citation Number: 19

Abstract

Abstract A new procedure for the synthesis of 3-acylcarbazoles useful for the construction of 6H-pyrido [4, 3-b] carbazoles is described starting from readily available gramines, or indoles. This methodology is exemplified by a synthesis of the anticancer alkaloid olivacine. Some discrepancies are noted between our results and those of other authors.