Abstract In the chromate oxidation of a partially acylated sugar derivative to form the corresponding uronic acid, acyl migration to the primary alcohol group is a frequent cause of interference. In contrast to more commonly employed ester substituents, the O-levulinoyl group is far less prone to migration during oxidations with Jones reagent (chromic-sulfuric acids). Examples described here include levulinoyl at O-5 of acylic and furanose ...
