Triene 22 was synthesized and converted by two different routes to the tetraaldehyde 27, the first “non-bridged” derivative of 1. An X-ray analysis of 27 reveals that the C C bond is twisted by 28.6°. Attempts to prepare 1 from 27 failed, thus far. Addition of t-butyllithium to 13, subsequent reaction with ethylene oxide and further reactions led to the highly strained tri-t- butylethylethylene 33; according to force field calculations 33 has the largest ...
![2,2,2',2',5,5,5',5'-octamethyl-[1,1'-bi(cyclopentylidene)]-3'-ene-3,4-diol Structure](https://image.chemsrc.com/caspic/003/108437-13-4.png)