Tetrahedron

Microwave assisted synthesis and crystal structures of 2-imidazolines and imidazoles

…, C Foces-Foces, ML Rodríguez, A Sánchez-Migallón

Index: de la Hoz, Antonio; Diaz-Ortiz, Angel; del Carmen Mateo, Maria; Moral, Monica; Moreno, Andres; Elguero, Jose; Foces-Foces, Concepcion; Rodriguez, Matias L.; Sanchez-Migallon, Ana Tetrahedron, 2006 , vol. 62, # 25 p. 5868 - 5874

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Citation Number: 38

Abstract

A series of 2-imidazolines and imidazoles has been synthesized using green synthetic methodologies. The preparation of 2-imidazolines was performed by cyclization of nitriles with ethylenediamine. The use of microwave irradiation in solvent-free conditions enabled 2- imidazolines to be obtained in high yields within short reaction times. Aromatization of imidazoles was performed under microwave irradiation in toluene and using Magtrieve™ ...