Synthesis of Phenanthro [9, 10??b] indolizidin??9??ones, Phenanthro [9, 10??b] quinolizidin??9??one, and Related Benzolactams by Pd (OAc) 2??Catalyzed Direct Aromatic …

S Yamashita, N Kurono, H Senboku…

Index: Yamashita, Satoshi; Kurono, Nobuhito; Senboku, Hisanori; Tokuda, Masao; Orito, Kazuhiko European Journal of Organic Chemistry, 2009 , # 8 p. 1173 - 1180

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Citation Number: 29

Abstract

Abstract Phenanthro [9, 10-b] indolizidin-9-ones, phenanthro [9, 10-b] quinolizidin-9-one, and related benzolactams were synthesized by benzolactam ring formation using Pd (OAc) 2-catalyzed direct aromatic carbonylation. This also constitutes a formal synthesis of the representative phenanthroindolizidine and-quinolizidine alkaloids (±)-tylophorine,(±)- antofine, and (±)-cryptopleurine.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 ...