Tetrahedron letters

A general and efficient CuI/BtH catalyzed coupling of aryl halides with thiols

AK Verma, J Singh, R Chaudhary

Index: Verma, Akhilesh Kumar; Singh, Jaspal; Chaudhary, Ritu Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7199 - 7202

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Citation Number: 119

Abstract

We report an exceptionally mild, general and efficient copper catalyzed cross coupling reaction of aryl bromides and thiols using 0.5 mol% CuI and 1mol% benzotriazole. Experimental simplicity, generality, functional group tolerance and low cost of the catalyst are advantages of the protocol.