Synthesis and antimicrobial activity of novel spirocompounds with pyrazolone and pyrazolthione moiety

…, PA Barve, V Suryanarayan

Index: Chande, Madhukar S.; Barve, Pravin A.; Suryanarayan, Vijay Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 1 p. 49 - 53

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Citation Number: 36

Abstract

Michael addition is one of the oldest well-known reactions, which involves the formation of a carboncarbon bond and has found extensive applications in organic synthesis. The reaction, usually carried out in basic conditions, deals with the addition of compounds containing active methylene group (donors) to activated systems (acceptors). More recently, the use of organometallics [1] and ionic liquids [2] has gained considerable importance to carry out ...