Supramolecular nanoparticle carriers self-assembled from cyclodextrin-and adamantane-functionalized polyacrylates for tumor-targeted drug delivery

…, X Wang, Q Zhang, M Khan, L Bai, ST Selvan…

Index: Ang, Chung Yen; Tan, Si Yu; Wang, Xiaoling; Zhang, Quan; Khan, Majad; Bai, Linyi; Tamil Selvan, Subramanian; Ma, Xing; Zhu, Liangliang; Nguyen, Kim Truc; Tan, Nguan Soon; Zhao, Yanli Journal of Materials Chemistry B, 2014 , vol. 2, # 13 p. 1879 - 1890

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Citation Number: 31

Abstract

The advancement of nanobiotechnology has led to the development of various techniques for addressing target-specific drug delivery issues. In this article, we successfully developed a supramolecular self-assembly approach for the fabrication of polyacrylate-based nanoparticles with simultaneous loading of the anticancer drug doxorubicin (DOX) for targeted delivery towards cancer treatment in vitro and in vivo. Two types of polyacrylates ...