Copper (II)??Catalyzed Aerobic Oxidative Coupling between Chalcone and 2??Aminopyridine via C H Amination: An Expedient Synthesis of 3??Aroylimidazo [1, 2??a] …

K Monir, A Kumar Bagdi, S Mishra…

Index: Monir, Kamarul; Kumar Bagdi, Avik; Mishra, Subhajit; Majee, Adinath; Hajra, Alakananda Advanced Synthesis and Catalysis, 2014 , vol. 356, # 5 p. 1105 - 1112

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Citation Number: 56

Abstract

Abstract: A simple and efficient protocol has been developed for the synthesis of 3- aroylimidazopyridines via copper (II) acetate-catalyzed aerobic oxidative amination. A library of 3-aroylimidazopyridines was synthesized from readily accessible chalcones and 2- aminopyridines with high yields and regioselectivity. The reaction proceeds through a tandem Michael addition followed by an intramolecular oxidative amination. The ...