The Journal of Organic Chemistry

Generation and [3+ 2] cycloaddition reactions of oxazoline N-oxides

SP Ashburn, RM Coates

Index: Ashburn, Stephen P.; Coates, Robert M. Journal of Organic Chemistry, 1984 , vol. 49, p. 3127 - 3133

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Citation Number: 49

Abstract

2, 4, 4-Trimethyloxazoline N-oxide (6a) and 2-ethyl-4, 4-dimethyloxazoline N-oxide (6b) have been prepared by condensation of 2-(hydroxyamino)-2-methyl-l-propanol hydrochloride (7) with triethyl orthoacetate and orthopropionate.[3+ 21 Cycloaddition reactions of nitrones 6a and 6b and the related 2, 5, 5-trimethylpyrroline N-oxide (12) with phenyl isocyanate, dimethyl acetylenedicarboxylate, methyl phenylpropiolate, ...