New carbocyclic potential minor groove binders were synthesised, using 3-nitrobenzoyl chloride and aliphatic α, ω-diamines with three, four and five methylene fragments. The half structures, compounds IV–VI can be compared to bis-amidines, compounds X–XII to bis- netropsin. All of the compounds were investigated antiproliferative and cytotoxic effects in the standard cell line of mammalian tumour MCF-7.
![3-amino-N-[4-[(3-aminobenzoyl)amino]butyl]benzamide Structure](https://image.chemsrc.com/caspic/492/618392-30-6.png)
